SLEEP-GREAT is a complete solution that helps you fall asleep quickly, stay asleep and enjoy deep, restorative sleep.

Description:

We should wake up well-rested every morning. Yet 43% of men and 55% of women say they have trouble falling asleep or staying asleep. We know how good it feels to fall asleep easily, to have a deep, restful sleep and to wake up feeling refreshed. More importantly, a good night's sleep is absolutely essential to our general well-being.

Sleep is part of our circadian rhythm - a cycle that depends on light and darkness, and enables the body to function normally. Melatonin - our "sleep hormone" - is secreted in response to darkness. Its secretion should be highest at night, to promote deep, restful sleep, and lowest during the day. Another hormone, cortisol - our "stress hormone" - acts in the opposite way to melatonin, inhibiting melatonin production to promote alertness and wakefulness.

The sleep cycle comprises five distinct stages. Stage 1 is when you fall asleep. Stage 2 is light sleep, when heart rate and brain waves begin to slow. Stage 3 is characterized by very slow delta waves in the brain. Stage 4 is the deepest state of non-REM sleep (NREM), when the body is in healing/repair mode. Stage 5 is when we dream, known as REM sleep.

This cycle should be repeated 4 to 6 times during a good night's sleep, which requires both getting enough sleep and repeatedly entering deep sleep (stages 4 and 5). When we have difficulty falling asleep, staying asleep or entering a deep sleep state, our overall health is significantly affected.

When we don't get enough sleep or our sleep is of poor quality, our ability to think clearly, learn and retain memories is significantly affected. Our immune system is weakened, leading to recurring colds and flus or difficulty overcoming infections. Our appetite and blood sugar levels are also affected. So it's not surprising that lack of sleep is associated with an increased risk of weight gain, heart disease and diabetes.

When we don't produce enough melatonin, we have higher cortisol levels, which can lead to anxiety, depression, irritability and difficulty coping with stress.

Melatonin

• Enhances the body's natural production of melatonin to promote sleep onset and deep, restful sleep.
• Helps trigger the body's sleep-wake cycle to remedy jet lag.

L-theanine

• Promotes sleep and reduces sleep disturbances.
• Reduces stress-related symptoms, low mood and anxiety, and improves cognitive function by targeting the brain's glutamate receptors, stimulating the release of GABA, serotonin and dopamine in the brain.

L-tryptophan

• Helps promote uninterrupted sleep and drowsiness, without causing lethargy on awakening.
• Increases serotonin production in the brain, reducing anxiety, improving mood and triggering sleep.

Gamma-aminobutyric acid (GABA)

• One of the brain's main inhibitory neurotransmitters, its role is to provide a sense of well-being and relaxation by shifting the nervous system from an anxious "fight or flight" state to a regenerative state of relaxation.
• Its soothing action makes it easier to fall asleep and regulates the phases of deep sleep, whether slow-wave or REM, offering better-quality sleep.

5-HTP 

• Crosses the blood-brain barrier and readily converts to serotonin once in the brain, improving mood, reducing anxiety and regulating sleep.

Japanese medlar (Eriobotrya japonica), fruit, 15:1 extract, 25% ursolic acid 

• Activates GABA receptors to prolong sleep.

Valerian (Valeriana officinalis), root, 4:1 extract, 0.05% valerenic acids 

• Improves sleep quality by increasing GABA in the brain, which promotes relaxation when falling asleep and regulates slow- and fast-wave sleep phases to favor deep sleep.

Skullcap (Scutellaria lateriflora), aerial parts, 4:1 extract 

• Reduces stress and anxiety by stimulating GABA receptors in the brain to promote relaxation.

Passionflower (Passiflora incarnata), aerial parts, extract 10:1 

• Passionflower has a mild sedative effect that considerably improves nervousness and anxiety by increasing GABA levels in the brain.

Schisandra (Schisandra chinensis), fruit, 10:1 extract 

• Acts as an adaptogen in the body, boosting our ability to manage stress and promoting feelings of relaxation by acting on serotonin pathways.

Each capsule contains : 

Melatonin. 5mg 

L-theanine 200mg 

L-tryptophan 50mg 

Gamma-aminobutyric acid (GABA) 50mg 

• 5-HTP (5-hydroxytryptophan, Griffonia simplicifolia, seed) 50mg

Japanese medlar (Eriobotrya japonica), fruit, extract 15:1, 25% ursolic acid (QBE 975 mg),65mg 

Valerian (Valeriana officinalis), root, 4:1 extract, 0.8% valerenic acid (QBE 200 mg),50mg 

Skullcap (Scutellaria lateriflora), aerial parts, 4:1 extract (QBE 200 mg),50mg 

Passionflower (Passiflora incarnata), aerial parts, extract 10:1 (QBE 400 mg),40mg 

Schisandra (Schisandra chinensis), fruit, 10:1 extract (QBE 250 mg),25mg 

Non-medicinal ingredients : 

Vegetable capsule shell (hypromellose), rice husk powder (Oryza sativa). 

Principal allergens : None 

Healthology does not use genetically modified ingredients. All ingredients are GMO / GMO-FREE. 

Recommended dosage: 

Adults: for sleep aid and all other uses: take 1 or 2 capsules with water once a day, before or at bedtime as required. For jet lag: take 1 or 2 capsules with water once a day at bedtime, during travel and at your destination, until your body adjusts to the new time zone or daily cycle. Do not drive or operate machinery for 5 hours after taking this product, which contains melatonin. Avoid taking capsules with alcohol or any other product that may make you drowsy. 

Duration of use: for prolonged use beyond 4 weeks, please consult a health care professional.

Contraindicated during pregnancy, while breast-feeding or in cases of scleroderma. Consult a health care practitioner prior to use while taking antiepileptic or antihypertensive drugs, immunosuppressants, drugs affecting mental status or increasing sedation, steroids, anticoagulants, carbidopa or drugs/supplements increasing serotonergic activity. These include, but are not limited to, L-tryptophan, S-adenosyl-methionine (SAMe), St. John's Wort, antidepressants, analgesics, over-the-counter cough and cold medicines containing dextromethorphan, antinauseants and migraine medications.

Consult a health care practitioner prior to use in the presence of cardiovascular, immune, liver or chronic kidney disease, hormonal or seizure disorders, asthma, depression, diabetes, hypoglycemia or migraine headaches. Consult a health care practitioner if symptoms persist or worsen. Discontinue use and consult a health care practitioner if signs of weakness, mouth ulcers, abdominal pain accompanied by severe muscle pain, or skin changes occur.

• Discontinue use and consult a health care practitioner if any of the following symptoms occur within a few hours of taking this product: change in mental status (e.g. agitation or confusion), increased heart rate, dilated pupils, loss of muscle coordination, headache, sweating, chills, allergy or gastrointestinal disturbances such as nausea, diarrhea or vomiting.

This product may cause drowsiness in some users. Exercise caution when operating heavy machinery, driving a motor vehicle or engaging in any activity requiring alertness. This product may cause diarrhea, vomiting and abdominal pain in some users.

Consult a health care practitioner prior to use if you have recently undergone or are about to undergo surgery. Keep out of reach of children.